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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa48c9d704d9759c112d1516bd4f6a195558b3f345077551c29f21f0dcef10ef' 
  AND token = 'HbG3EFFZEb9sYPRB0tGe/eqjm5pC4nDn0LUOJ/vHc/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}