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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b56e508e3184c54da0aed967f176a4de9ff4ecce19bcc3709cf7a285374799' 
  AND token = 'VGYpu5N9uCzPSciMh6FU4W+W0Cx5tz6feHhVkBY1E1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}