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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4561110a1109e3fc711fce4ac4c3f57561a3869bdc6c7d3e7e474fd23f4e1ea4' 
  AND token = 'ijkWlmVXhw/1GeeBgA/kQ0y9mzF8cUCOUfzk5Z0+Naw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}