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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68c779d7a3fee65be1481a83d838f047b7e0400af36c116d568ed63ae0143dd0' 
  AND token = '4Di8SDd8VEtDMTjDaSRKF8kN0/XgQu8UydE8kiALU9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}