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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a06d157037ad51d36ac977b293ecfe43f0eced0613b4de528eb7184dfbf2b248' 
  AND token = 'D2mZHrg9S0pPg2UwPBrkDtDf2E1H2xX0Jj6VZuzWYRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}