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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce609ea0b8a738a7e8c5335c51a1f7aad35c87f1479b022de58ef5525fb7f0b' 
  AND token = 'MK/rYO5EAUlxlxTFRdVVmJA5u3TNdSIWB2TsmDQX+Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}