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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c1544bcf51cee88a78f8d15c1b13d5459f2783ef259787d30d31ef071f1a295' 
  AND token = '3Y4J6ZeEejphiG4gWonWj4AVZ6NQxAcPXM5ZhFMG9+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}