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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b1e4e73536dbba85da4463c65a0fac47fc9b5f3d449a4bea594e90d18bb3544' 
  AND token = 'LFIJ9T+oOAZ62+GSEqQeFHo0VXSdU3z4D3X2+Y82+uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}