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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b01ca705ac72898ef95f7e30cdb76a9021703d59b4c917166f349ee601d739' 
  AND token = 'Mj4zXUOs0hijeyqqliqo+oX6oH0RaiOV9AqdiOfFVjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}