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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282437061d9188f84c57b865d5257fb61da618db5bb2b880a4c6f4a9dbe52443' 
  AND token = 'Zbnp6809HCb7DRqcp+Ft7f+u+wk8lEr3Gw6UJzsXRSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}