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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc1b5999c1a46faf767c87a60a897e54ae16a3426368d36b59db7275dadd372' 
  AND token = 'HCLIchGkXI+70qejOu0go6idUH5DdoS2x9kmcWv+4eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}