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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdbc89c3b4e88c6aa4fe36ec395dcbb79493c779ccb0da808df283fe4a78fc00' 
  AND token = 'vaGUy745jMAS4bBdEvxU5BLhJQQY7F+k1u2ZSWrw2Ks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}