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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d2ceea3e9324e6ce2e4f6c64c48b1a06a6f17031e936f8db2b279c2a713953' 
  AND token = 'vgvTPjC2x/3a7qImAhAauign7BPi57an36vKH/Kfhp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}