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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0587d943e022603921d78222914125108722f336c430f8f8443f8f1e6577ab09' 
  AND token = 'aIEsAc1fLGvTOvk7V9dhRNZhwJN0Mtiz86pDHS7qhfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}