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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821e980ec1c7f681d4c9dfa66bb07873fcc20e2f1a453ccde1ef8a0ca887dec5' 
  AND token = 'EraxQV03qxE3Xx9CAI+qIgTRxXigSJbjHE+iX7JYCAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}