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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6586c178f5f87f1ef483be70ff7137c326d4edc034bfd5f6e087f1699e204053' 
  AND token = 'oz534biMoyvgoDD9t+hYwMA6xnRUwzCFzMrdhHnG2Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}