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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9cb8dbe029c56272e4ad9e87d3c1a9f565b03ad42e19da3c8b9cd22eb91cd3' 
  AND token = 'VfMZ4ghRja+WbzWj+HMiyyhAlwArfXfz+rQMyQ0W1ew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}