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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '531d13933edd46994799f146b41ef6474e033d9611b5859ba0bca1d38869ce2c' 
  AND token = 'nvTv5AVKaGhaFR/ehAMyDkGoKaIQefuJi8STCOGSUuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}