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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e835a65625676a7d2a4ee7838a6b19c5e762b0c61e8e2e4bd04de6c463dadeb8' 
  AND token = '3quTz2oyJSCZ8phQCAYxdR0IY7HPw0vAE6+r8mfqtwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}