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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e521426c1ab307e47ae7e1a8c9d1cca80c00f2b604b3bca681861bb314aa0cb' 
  AND token = 'jSt7v7iUz8+6DzsmcI9wJdrU4saPcb2c9QKT+sWBuBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}