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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b4044e59f4ac5d43024e9bdc80536f256ba8693db9435908540cf20b6d8df2' 
  AND token = 'XwW54d9WUr3TYXs+oZA7ZMEQv0gWzjOmM4tLag0pKsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}