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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b23f4a061285f42b7c61fade4124d9314a5bcde49fca7a444aeedcaf7135e553' 
  AND token = 'aVrIgTMuGvoiGZAoczRvucAotA8Zkv45Y+fp5K2ClVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}