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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '674b00231705b82237c1c043612da39edd39103edc5415b36211f271956539fa' 
  AND token = 'jcZMRJ+QpcUEO1/SgLQyA+4ReFRoJSD7QJO2da+YqNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}