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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05bb106d53c6022e3f21d5d1cc16098d6626c6ecc4b5b1c9d202dca74a4b3270' 
  AND token = 'Z+It+j2XjCaLynHJ/BTM+ENC1zqW/wYatSqfn/c9BN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}