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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd37fa25de44eec63e06ab77d7ae3ea6a1a685a4714d206138b81fc3e53a77d2e' 
  AND token = 'oHrtDn13j3MwhkCtgc4H6hqm9Ex3OCCRKXJ73bqpwTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}