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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a21ac39ff646a0f0eb38538cdbaf9c9fa156cf94db911f56f8319007d1a0f523' 
  AND token = 'CABco+o68XQHn1Xnd+lOnEesSTQCPxiB6cbHj6aCnvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}