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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a438eb84ed943bebcb47eb1a5c907e55be40f54cb557bf731aa62e40b61e1796' 
  AND token = '0LOQe2bnnlpNQ2qDb57XlePich+3MG3rqqNuDksVsZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}