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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c932f85a0bddc97a21483a613497e73d434ec0dc96ef5a23542748e6887b370' 
  AND token = 'JWJ8qTh1g0DTzQZIUhiD2pIW0hVULPVaSymKLPV6Ico=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}