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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0e8e8da52852458d39dfec46a71976085365b377f7d73c27b9fbc8af08924e' 
  AND token = 'wyzdPB3KL5tMkcyU3u/FEHn22fVHuGi9jIFXkDSlqSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}