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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8c9c81d5e2e369bcf6ae321d70fcb45856372a38c31a4d2db9034ab33edc66' 
  AND token = 'qlDMwUfMrHbnhuphNBFrkMR6ZbOsMyv8ErNRTX18Z3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}