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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f2dccb4a6b1e8f6605e710d13072ddd2a4948fa09c50b26e567611ac5f1789' 
  AND token = '4AeYU/9AjfnToi3ohiCA7qZqK5ZOZE+tuDlNIuGeUm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}