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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449685c97bf4098b028bebeeeb1273da36ed2ed5681b3e6dbac7f4de97e86cda' 
  AND token = 'dITumSyQUPvI3elkz/8xpZrCvN66KQmTpHXEhF12odw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}