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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab1185e347a199b4a1cacf436948174aabe7e5731af95ff4bee09194fead21ff' 
  AND token = 'TZ1cF1QPs1Jo1Dr4zFWZVVQr6G+s2ZDSfr9+8Fk4sXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}