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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f81e1449b6a4eeac02f0c36ab7fcd548ba85a7622be98e3b77e048336afb8ea' 
  AND token = 'nSx+/rTn+0gXIHTADHWEpvvq2UNe1Zfqow43y0hvNqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}