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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6b6df7af7270c5104cab81ff05600cb60d1115a20378a01eabac4ba86340aa' 
  AND token = 'j0lVEfkq4atwZpnL8zyTnsM+5BcGUN9IeIjTPoqgm4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}