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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59d92ae4a5a749b85e3455afe0f1395a7d9fc1fde71ed26bb28097e20d12f0cf' 
  AND token = '65/VgD9IDoe/rwI5B0YICEquaKlQoSYBi6GlZXI7MYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}