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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efad7426043aaead5eff4e851a1d3ca38cd5cebebc010003a4de5ab1d4f2d640' 
  AND token = '+Fm4YZ9X9ME2F2PLsYhuqnQg3cW9D+NNPWCtWdJT5VY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}