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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be7c081fcc2116b0ad3fe8ba278292ad5561e21b48a011e0a732db60947888f4' 
  AND token = 'zI3+y/spIfjar16y9roVnbklRAj7EKSe2uhTKeIM7CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}