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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee533f74ce39f9ec0e567b924c2e8495ceb0095337823d90dabe030a5dc99250' 
  AND token = 'zH3UfpH7RVGJKNdeqLnjIlicM09ZZB9Nz6JYdFnXODc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}