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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '180c793945367d76d1a2c13ee17c64637e02344b9528380447165305616bad63' 
  AND token = 'tN4doyeVUeXT7vgwoKnJVVySGkoCVyF3iiNUBGdkA+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}