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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd772fa4e445f67fa8a0c1bf69d685ad2b695a09415a50c8054737b718a949d4c' 
  AND token = 'j0ayJ04BYcIqs7SU03nA2QGvh3Tcnm/0ZJXPndD28Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}