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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0162f1cb15de91bc774b449d277bcd10276e23fe821f1420db1c2948e2a1bc' 
  AND token = 'JKFFObM0DcNfksZnvx35KghvjHSYg4wIvDd4oiF/50Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}