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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97c88f21376e5d3aceb15aef1ca8db8634ce58caa25a6703e2bc69418aad4164' 
  AND token = '+PLIEqpRAAIvIk/Z6diO3qFCh1pQ7XFRJBFSr9xYJYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}