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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9c05496632514e7e0cc5d610305922a5f61eda7e282b3e6995186aa3170613' 
  AND token = 'R8I/qytjjIE439IA10vqr5//K/iKPnzv71VcXEmsuho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}