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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '677ecd80b2c28c591c133d585e0cd5332bfad7260c25d5a383060863a8f9a001' 
  AND token = '8u3d5VYs2jI23mhAA4BDVbzohvfanbvDhpZ0OC8ZNL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}