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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39764fa1acd236f1580cbc1eb0521123e43f0abcb0885e3bce6d60acb80f1052' 
  AND token = 'EFmMGCtxHJqCGaB5W5Stw3Xzf1bihc5ni7L3PTy9C+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}