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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4519786105a7314ddcd0a171f830b2722a8114a1c5392a6f86cdd56f24a620c' 
  AND token = 'IQNaSmI8NoM7OBFapTek9DfyNla8JKeMOEoasBFjGlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}