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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ca41e68aa37c2eb223ef477c2d30d3d027eaaa68cdf26419cd8cd31ac7058e' 
  AND token = '1quo8iqO+V7yY4G8WdtyDDC0gxbFDdSE3qUBvBYQD/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}