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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de02165d2818c7920c06e5240a45a98efe1e2496ba3560ebb78a3a8762b56e6' 
  AND token = 'KoHpUEAA6jpwpz1/8A8pzhnWkQdiQ6XAcEA0NcHpIk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}