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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6d5c6653f753c554ad8c44d6f1ecb3a01cefc91ed51d7fc7748627f491801b' 
  AND token = 'T4MqyfCuHrz3mXD7jld+npm1Yk6xcFjWxbQIR8n4YEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}